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Table 2 Cardiometabolic risk factors at three years postpartum in women and offspring at age 3

From: The association of breast feeding for at least six months with hemodynamic and metabolic health of women and their children aged three years: an observational cohort study

Anthropometric and hemodynamic variables at three years

 

Breastfed for at least six months (n = 70)

Did not breastfeed for at least six months (n = 74)

Effect Size (MD, 95% CI)^

 BMI (kg/m2)

28.4 (8)

31.6 (10.2)

-3.34 (6.5, -0.2)

 Fat mass (kg)

29.1 (17.3)

36.4 (19.3)

1.2 (-3.7, 6.1)

 Waist circumference (cm)

88.6 (20.6)

95.9 (20.5)

-9.1 (-17.8, -0.2)

 Systolic blood pressure (mmHg)

119.0 (12.7)

122.5 (14.6)

-6.5 (-10.8, -2.2)

 Diastolic blood pressure (mmHg)

66.9 (9.3)

70.2 (11.3)

-5.1 (-8.3, -1.7)

 Mean arterial pressure (mmHg)

80.8 (9.8)

85.1 (14.1)

-5.2 (-9.1, -1.1)

 Augmentation Index (%)

53.1 (18)

56.7 (22.8)

3.4 (-4.3, 9.1)

 Central systolic blood pressure (mmHg)

109.4 (11.9)

111.9 (13.9)

-4.9 (-9.1, -0.9)

 Central diastolic blood pressure (mmHg)

69.6 (9.4)

73.1 (11.8)

-5.4 (-8.7, -2.0)

Fasting blood values

 

Breastfed for at least six months (n = 24)

Did not breastfeed for at least six months (n = 30)

Effect Size (MD, 95% CI)^

 Fasting glucose (mmol/L)

4.7 (0.5)

4.7 (0.5)

-0.163 (-0.4, 0.1)

 Insulin(mU/L)*

8.1 (3.1)

13.2 (9.2)

-3.9 (-9.0, 1.2)

 HOMA-IR*

1.7 (0.6)

2.8 (2.1)

-0.04 (-0.2, 0.19)

 Triglycerides (mmol/L)**

0.9 (0.4)

1.3 (7.5)

-0.57 (-0.95, -0.19)

 HDL-C (mmol/L)

1.4 (0.8)

1.4 (0.4)

0.202 (0.007, 0.396)

 LDL-C (mmol/L)

1.2 (0.3)

2.6 (0.7)

0.03 (-0.36, 0.43)

 Total Cholesterol/HDL ratio

3.2 (0.8)

4.8 (5.3)

-0.07 (-2.4, 2.3)

 Non-HDL Cholesterol

3.1 (0.8)

3.2 (0.8)

-0.19 (-0.64, 0.26)

 Total Cholesterol (mmol/L)

4.3 (0.9)

4.4 (0.8)

0.04 (-0.48, 0.55)

 C-Reactive Protein

3.8 (4.8)

3.4 (2.5)

0.67 (-1.5, 2.9)

 

Offspring who were breastfed for at least six months (n = 68)

Those who were not breastfed for at least six months (n = 71)

Effect Size (MD, 95% CI)^

 BMI SDS^

55.6 (29.8)

58.4 (31.7)

-1.7 (-9.1, 12.6)

 Waist circumference*

51.1 (3.5)

51.8 (4.5)

-0.6 (-2.1, 0.8)

^^

(n = 38)

(n = 34)

 

 Systolic blood pressure (mmHg)

101.9 (12.1)

96.1 (18.5)

6.8 (-1.3, 15)

 Diastolic blood pressure (mmHg)

58.8 (10.5)

58.1 (15.8)

1.3 (-5.7, 8.3)

 Mean arterial pressure (mmHg)

73.1 (13.3)

71.1 (18.3)

4.2 (-4.1, 12.6)

 Augmentation Index (%)

87.2 (38.4)

98.3 (52.5)

5.4 (-9.1, 19.9)

 Central systolic blood pressure (mmHg)

94.2 (12.4)

91.6 (20.3)

2.0 (-5.6, 9.7)

 Central diastolic blood pressure (mmHg)

62.6 (10.1)

61.2 (13.0)

2.3 (-4, 8.7)

  1. Bold indicates significant effect size
  2. The reduced sample size for maternal blood tests was due to noncompliance of participants who did not complete respective blood tests
  3. *P-value = 0.001 for univariate analysis
  4. **P-value = 0.006 for univariate analysis
  5. ^based on univariate linear regression
  6. ^BMI SDS is adjusted for age and sex [23], all other outcomes are adjusted for child age
  7. ^^The sample size for child hemodynamic variables is smaller due to noncompliance with the USCOM BP +