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Table 4 Differences between time 0 and 6 months in concentrations of IgG and IgA anti-SARS-CoV-2 antibodies in serum and breast milk according to the type of vaccine received

From: Development of SARS-CoV-2 specific IgG and IgA antibodies in serum and milk with different SARS-COV-2 vaccines in lactating women

Antibody

Vaccine

n

Time 0

AU

Mean ± SD

6 months

AU

Mean ± SD

Paired t test

df

p

Serum IgA (AU/mL)

BNT162b2

39

0.00–0.49

0.00–0.16

   

0.14 ± 0.08

0.02 ± 0.03

7.74

38

< 0.01

mRNA-1273

11

0.004–0.42

0.00–0.15

   

0.14 ± 0.14

0.05 ± 0.05

2.22

10

0.05

Serum IgG (AU/mL)

BNT162b2

39

0.09–0.60

0.10–0.52

   

0.31 ± 0.12

0.25 ± 0.11

2.00

38

0.05

mRNA-1273

11

0.15–0.51

0.21–0.53

   

0.31 ± 0.08

0.34 ± 0.10

0.67

10

0.52

Breast milk IgA (AU/mL)

BNT162b2

39

0.00–0.56

0.00–0.16

   

0.12 ± 0.13

0.05 ± 0.04

3.42

38

0.00

mRNA-1273

10

0.00–0.25

0.02–0.32

   

0.12 ± 0.09

0.08 ± 0.10

1.73

10

0.11

Breast milk IgG (AU/mL)

BNT162b2

39

0.07–0.619

0.03–0.60

   

0.40 ± 0.11

0.15 ± 0.13

11.40

38

< 0.01

mRNA-1273

11

0.23–0.60

0.05–0.66

   

0.46 ± 0.09

0.22 ± 0.17

4.80

10

0.00

  1. Abbreviations: AU arbitrary units, SD standard deviation, df degrees of freedom