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Table 3 Odds ratios (ORs) of childhood underweight from 1 to 6 years of age according with infant feeding modalities

From: The association between breastfeeding and childhood obesity/underweight: a population-based birth cohort study with repeated measured data

 

No. of Participants

N (%) of Underweight

ORs and 95 CIs

Model 1

Model 2

Model 3

1 Years old

 xclusive formula feeding

5934

30 (0.5)

1.00

1.00

1.00

 Mixed feeding

35,374

106 (0.3)

0.75 (0.48, 1.17)

0.60 (0.35, 1.02)

0.44 (0.21, 0.91)

 Exclusive breastfeeding

18,256

73 (0.4)

0.91 (0.57, 1.46)

0.73(0.42, 1.27)

0.64 (0.31, 1.32)

Ptrend

  

0.793

0.659

0.863

2 Years old

 Exclusive formula feeding

5934

33 (0.6)

1.00

1.00

1.00

 Mixed feeding

35,374

171 (0.5)

0.87 (0.60, 1.26)

0.77 (0.49, 1.21)

0.78 (0.40, 1.49)

 Exclusive breastfeeding

18,256

98 (0.5)

0.96 (0.65, 1.42)

0.85 (0.52, 1.38)

0.86 (0.44, 1.68)

Ptrend

  

0.835

0.830

0.962

3 Years old

 Exclusive formula feeding

5934

70 (1.2)

1.00

1.00

1.00

 Mixed feeding

35,374

290 (0.8)

0.68 (0.52, 0.88)

0.59 (0.42, 0.82)

0.53 (0.33, 0.86)

 Exclusive breastfeeding

18,256

159 (0.9)

0.72 (0.54, 0.95)

0.72 (0.51, 1.03)

0.55 (0.33, 0.91)

Ptrend

  

0.151

0.528

0.131

4 Years old

 Exclusive formula feeding

5934

77 (1.3)

1.00

1.00

1.00

 Mixed feeding

35,374

382 (1.1)

0.82 (0.64, 1.05)

0.84 (0.64, 1.10)

0.88 (0.51, 1.50)

 Exclusive breastfeeding

18,256

197 (1.1)

0.82 (0.63, 1.07)

0.85 (0.63, 1.14)

0.95 (0.55, 1.64)

Ptrend

  

0.275

0.935

0.895

5 Years old

 Exclusive formula feeding

5934

94 (1.6)

1.00

1.00

1.00

 Mixed feeding

35,374

376 (1.1)

0.66 (0.53, 0.83)

0.62 (0.46, 0.83)

0.65 (0.40, 1.07)

 Exclusive breastfeeding

18,256

209 (1.1)

0.72 (0.56, 0.91)

0.71 (0.52, 0.97)

0.83 (0.51, 1.37)

Ptrend

  

0.090

0.302

0.735

6 Years old

 Exclusive formula feeding

5934

111 (1.9)

1.00

1.00

1.00

 Mixed feeding

35,374

556 (1.6)

0.83 (0.67, 1.02)

0.87 (0.67, 1.14)

0.88 (0.57, 1.37)

 Exclusive breastfeeding

18,256

303 (1.7)

0.88 (0.71, 1.09)

0.97 (0.73, 1.29)

1.16 (0.75, 1.81)

Ptrend

  

0.543

0.673

0.085

  1. Model 1: univariate analysis
  2. Model 2: adjusted for sex, gestational age, birth weight and maternal characteristics (age, education, smoking status, and gestational diabetes in term pregnancy)
  3. Model 3: adjusted for covariates in Model 2 and also for maternal prepregnancy body mass index
  4. Testing trend for differences from exclusive formula feeding to mixed feeding to exclusive breastfeeding in each category