Feeding in the first six months of life is associated with the probability of having bronchiolitis: a cohort study in Spain

Gómez-Acebo, Inés; Lechosa-Muñiz, Carolina; Paz-Zulueta, María; Sotos, Trinidad Dierssen; Alonso-Molero, Jéssica; Llorca, Javier; Cabero-Perez, María J.

doi:10.1186/s13006-021-00422-z

International Breastfeeding Journal

Table 2 Relationship between type of feeding and diagnosed with at least one episode of bronchiolitis

From: Feeding in the first six months of life is associated with the probability of having bronchiolitis: a cohort study in Spain

	Hospital discharge to 12th month				2nd to 12th month		4th to 12th month			6th to 12th month
Category	no. bronchiolitis / children at discharge	aOR (95% CI)	p	no. bronchiolitis / children at 2nd month	aOR (95% CI)	p	no. bronchiolitis / children at 4th month	aOR (95% CI)	p	no. bronchiolitis / children at 6th month	aOR (95% CI)	p
Type of feeding
Infant formula only	61/163	1(ref.)	.	96/295	1(ref.)	.	118/383	1(ref.)	.	125/477	1(ref.)	.
Mixed (breastfeeding and infant formula)	70/264	0.60 (0.39, 0.94)	0.02	44/179	0.69 (0.44, 1.06)	0.09	40/162	0.77 (0.49, 1.19)	0.24	36/181	0.73 (0.47, 1.14)	0.17
Breastfeeding	123/479	0.61 (0.41, 0.91)	0.02	105/418	0.73 (0.51, 1.05)	0.09	73/348	0.61 (0.43, 0.89)	0.01	42/234	0.67 (0.44, 1.02)	0.06
Change in type of feeding
Infant formula only				61/162	1(ref.)	.	92/296	1(ref.)	.	107/383	1(ref.)	.
Previously breastfed, currently infant formula only				35/134	0.58 (0.35, 0.98)	0.04	26/87	0.95 (0.55, 1.64)	0.85	18/94	0.67 (0.37, 1.22)	0.19
Previously exclusive breastfeeding or any breastfeeding, currently any breastfeeding				44/179	0.54 (0.33, 0.89)	0.01	40/162	0.76 (0.48, 1.20)	0.24	36/181	0.68 (0.43, 1.07)	0.10
Exclusive breastfeeding since birth				105/418	0.58 (0.38, 0.88)	0.01	73/348	0.61 (0.41, 0.90)	0.01	42/234	0.62 (0.40, 0.95)	0.03
Duration of breastfeeding
No breastfeeding				68/181	1(ref.)	.	63/181	1(ref.)	.	57/181	1(ref.)	.
Stop breastfeeding before the X^a month				28/109	0.57 (0.33, 1.00)	0.05	57/216	0.64 (0.41, 1.02)	0.06	77/321	0.69 (0.45, 1.06)	0.09
Continuing to breastfeed in the X^a month				146/576	0.55 (0.38, 0.81)	0.002	108/469	0.53 (0.36, 0.80)	0.002	66/364	0.45 (0.29, 0.70)	< 0.001

adjusted for maternal smoking, maternal occupational status, twin pregnancy, gestation length, birth order, daycare attendance and months with which he begins kindergarten
aOR Adjusted Odds Ratio
CI Confidence Interval
^a X is the time month

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