Table 3 Clinical outcomes of extremely low birthweight infants between the OAC group and control group at the time of discharge

NEC (Bell stage 2 or 3), n (%)

1 (7.14)

1 (9.09)

-^a

1.00

0.79(0.06, 11.20)

1.95%(− 28.01, 36.41%)

Bell stage 2, n (%)

1 (7.14)

0 (0.00)

-^a

1.00

-^c

7.14%(−25.71, 35.83%)

Bell stage 3, n (%)

0 (0.00)

1 (9.09)

-^a

0.44

-^c

9.09%(−19.02, 42.88%)

Late onset sepsis, n (%)

0 (0.00)

4 (36.36)

-^a

0.03

-^c

36.36%(0.42, 68.39%)

Clinical sepsis, n (%)

0 (0.00)

1 (9.09)

-^a

0.44

-^c

9.09%(−19.02,42.88%)

Proven sepsis, n (%)

0 (0.00)

3 (27.27)

-^a

0.07

-^c

27.27%(−6.1, 60.68%)

Patent ductus arteriosus, n (%)

6 (42.86)

8 (72.73)

-^a

0.23

0.59(0.29, 1.19)

29.87%(−13.4, 61.11%)

Intraventricular hemorrhage (grade 3 or 4), n (%)

1 (7.14)

6 (54.54)

-^a

0.02

0.13(0.02, 0.93)

47.40%(5.9, 75.55%)

Periventricular leukomalacia, n (%)

0 (0.00)

0 (0.00)

–

–

–

–

Bronchopulmonary dysplasia, n (%)

3 (21.43)

3 (27.27)

-^a

1.00

0.79(0.20, 3.16)

5.84%(−29.98, 42.77%)

Retinopathy of prematurity, n (%)

7 (50.00)

4 (36.36)

-^a

0.69

1.38(0.54, 3.52)

13.64%(−27.59, 48.99%)

Cholestasis, n (%)

1 (7.14)

3 (27.27)

-^a

0.29

0.26(0.03, 2.18)

20.13%(−14.81, 54.22%)

Age of achieving full enteral feeding (d), mean ± SD

34.07 ± 8.15

48.55 ± 22.00

−2.28 (df23)

0.03

−14.47(−27.60, − 1.35)

-^b

Age of achieving full oral feeding (d), mean ± SD

61.07 ± 15.13

62.91 ± 23.89

−0.24 (df23)

0.82

−1.84(− 18.03, 14.35)

-^b

Rate of weight gain (kg.d), mean ± SD

17.75 ± 3.69

16.38 ± 3.11

0.99 (df23)

0.33

1.37(−1.51, 4.25)

-^b

Indwelling time of PICC (d), mean ± SD

36.93 ± 11.53

40.54 ± 14.59

−0.69 (df23)

0.50

−3.62(−14.41, 7.18)

-^b

Days of mechanical ventilation (d), mean ± SD

6.07 ± 6.49

14.64 ± 28.84

−1.08(df23)

0.29

−8.56(−24.93, 7.80)

-^b

Days of noninvasive ventilation (d), mean ± SD

38.71 ± 17.88

32.00 ± 15.73

0.98 (df23)

0.34

6.71(−7.43, 20.86)

-^b

Length of hospitalization, mean ± SD

71.00 ± 17.37

74.64 ± 20.60

−0.48 (df23)

0.64

−3.64(−19.34, 12.07)

-^b