Administration of breast milk cell fractions to neonates with birthweight equal to or less than 1800 g: a randomized controlled trial

Table 2 In-hospital outcomes according to the birthweight in neonates who received BMCFs and the control group

In-hospital outcomes*	Birthweight 1500-1800 g		OR (95% CI)‡	DF‡	P †	Birthweight < 1500 g		OR (95% CI)‡	DF ‡	P †
In-hospital outcomes*	Received BMCFs (N = 33)	Control (N = 38)	OR (95% CI)‡	DF‡	P †	Received BMCFs (N = 42)	Control (N = 43)	OR (95% CI)‡	DF ‡	P †
Hospital length of stay (day)	14.7 ± 7.1	18.3 ± 13.6		69	0.35	41.6 ± 25.7	33.4 ± 25.4		83	0.09
Discharge weight (grams)	1683.7 ± 113.6	1683.6 ± 166.5		67	0.38	1675.1 ± 245.4	1744.3 ± 289.1		66	0.15
Mortality	1 (3.0%)	1 (2.6%)	1.16 (0.07, 19.24)		0.92	4 (9.5%)	13 (30.2%)	0.24 (0.07, 0.82)		0.02
Intubation period (day)	1.2 ± 1.5	1.5 ± 2.8		67	0.82	4.7 ± 9.0	6.2 ± 8.2		83	0.07
NIV period (day)	3.5 ± 2.7	4.2 ± 4.0		69	0.64	14.1 ± 14.3	9.3 ± 12.4		82	0.06
NEC	1 (3.0%)	2 (5.3%)	0.56 (0.05, 6.50)		0.64	3 (7.1%)	5 (11.9%)	0.57 (0.13, 2.55)		0.46
BPD	0	2 (5.3%)	–		0.18	14 (33.3%)	8 (18.6%)	2.19 (0.80, 5.95)		0.12
ROP	1 (3.0%)	3 (7.9%)	0.36 (0.04, 3.68)		0.37	20 (48.8%)	17(39.5%)	1.46 (0.61, 3.46)		0.39
Positive blood culture	1 (3.0%)	1 (2.7%)	1.12 (0.07, 18.73)		0.93	3 (7.3%)	5 (11.9%)	0.58 (0.13, 2.62)		0.48

* Data are presented as mean ± standard deviation, number (%)
† Statistically significant P-values are bolded. Categorical variables were compared using the chi-square test and numerical variables were compared using the Mann–Whitney U-test
‡ Odds ratio (OR) and 95% confidence interval (95% CI) are presented for categorical variables, and the degree of freedom (DF) is presented for numerical variables
BMCFs breast milk cell fractions, BPD bronchopulmonary dysplasia, DF degree of freedom, NEC necrotizing enterocolitis, NIV non-invasive ventilation, OR odds ratio, ROP retinopathy of prematurity

ISSN: 1746-4358