Skip to main content

Table 2 Cord blood and early breast milk levels of Sirtuin3 (Sirt3), 8-hydroxy-2-deoxyguanosine (8OHdG), brain-derived neurotrophic factor (BDNF) and serotonin (5HT) of mothers giving birth at term vaginally or by Caesarean section and those delivering preterm (median with 25th and 75th centiles)

From: Effects of perinatal factors on sirtuin 3, 8-hydroxy-2′- deoxyguanosine, brain-derived neurotrophic factor and serotonin in cord blood and early breast milk: an observational study

  SIRT 3 (ng/ml) 8-OHdG (pg/ml) BDNF (ng/ml) 5-HT (ng/ml) Compared Groups
I. Venous cord blood   p = 0.001**
X2 = 13.61
  p < 0.001**
X2 = 21.82
  p < 0.001**
X2 = 38.55
  p = 0.09
X2 = 4.91
1–2-3
 1. Vaginal birth at term (N = 27) 0.27 (0.23;034) p = 0.224
Z = -1.22
7.42 (0.05;14.41) p = 0.54
Z = -0.61
77.94 (64.03;119.09) p = 0.007**
Z = -2.72
90.96 (55.53;110.64) p = 0.57
Z = -0.57
1–2
 2. Caesarean section at term (N = 29) 0.24 (0.18;0.31) p = 0.02*
Z = -2.41
8.41 (1.34,15.48) p < 0.001**
Z = -3.68
57.22 (54.76;76.80) p < 0.001**
Z = -4.68
73.55 (56.59;107.29) p = 0.10
Z = -0.1.64
2–3
 3. Preterm birth (N = 28) 0.20 (0.15;0.24) p < 0.001**
Z = -3.62
21.10 (11.63;26.87) p < 0.001**
Z = -4.28
36.22 (24.83;47.17) p < 0.001**
Z = -5.40
58.39 (45.52;90.70) p = 0.04*
Z = -2.07
1–3
II. Breast milk   p = 0.184
X2 = 3.39
  p = 0.01**
X2 = 9.55
  p = 0.03*
X2 = 7.23
  p = 0.02*
X2 = 8.03
1–2-3
 1. Vaginal birth at term (N = 27) 0.34 (0.17;1.27) p = 0.06
Z = -1.94
13.29 (4.15;30.45) p = 0.09
Z = -1.68
0.97 (0.76;1.11) p = 0.68
Z = -0.42
14.69 (6.13;24.10) p = 0.48
Z = -0.70
1–2
 2. Caesarean section at term (N = 29) 1.72 (0.26;5.25) p = 0.80
Z = -0.25
7.76 (3.20;17.6) p = 0.002**
Z = -3.11
0.24 (0.20;0.94) p = 0.02*
Z = -2.39
8.65 (3.43;23.35) p = 0.01*
Z = -2.50
2–3
 3. Preterm birth (N = 28) 2.19 (0.23;5.77) p = 0.22
Z = -1.23
15.30 (10.85;35.97) p = 0.24
Z = -1.17
0.03 (0.02;0.11) p = 0.008**
Z = -2.65
25.82 (11.04;34.72) p = 0.02*
Z = -2.25
1–3
I-II. Cord blood and breast milk
 1. Vaginal birth at term (N = 27)   p = 0.08
Z = -1.75
  p = 0.01*
Z = -2.46
  p = 0.03*
Z = -2.20
  p < 0.001**
Z = -4.37
 
 2. Caesarean section at term (N = 29)   p < 0.001**
Z = -3.80
  p = 0.61
Z = -0.51
  p = 0.02*
Z = -2.37
  p < 0.001**
Z = -4.76
 
 3. Preterm birth (N = 28)   p < 0.001**
Z = -4.00
  p = 0.70
Z = -0.38
  p < 0.001**
Z = -4.78
  p < 0.001**
Z = -4.74
 
  1. Comparisons between three groups (1,2,3) by Kruskal-Wallis test, between two groups (1–2 or 2–3 or 1–3) by Mann-Whitney U test and between venous cord blood and breast milk (I-II.) were done by Wilcoxon test
  2. **= p < 0.01, *= p < 0.05