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Table 4 Concentration of bioactive factors presented in the lipid phase of human milk during the first 6 months of lactation [pg/ml]

From: Distribution of bioactive factors in human milk samples

Factors

Lipid phase [L]

Water fraction [L-WF]

Lipid fraction [L-LF]

1–3 months

4–6 months

p- values

1–3 vs 4–6 mo

1–3 months

4–6 months

p- values

1–3 vs 4–6 mo

CD40

22.87 ± 7.36

34.11 ± 6.67

0.019

22.98 ± 7.87

29.80 ± 0.01

0.1330

EGF

828.48 ± 480.11

1851.26 ± 456.69

< 0.0001

375.25 ± 129.18

669.11 ± 197.70

< 0.0001

MCP-1

13.02 ± 3.49

21.41 ± 9.71

0.0245

5.07 ± 0.69

10.67 ± 6.01

0.0020

RANTES

3.13 ± 0.73

4.34 ± 0.59

< 0.0001

3.65 ± 1.86

2.37 ± 0.0

0.2031

  1. CD40 cluster of differentiation 40; EGF epidermal growth factor; MCP-1 macrophage chemokine protein-1; RANTES regulated on activation, normal T cell expressed and secreted; mo months