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Table 4 Concentration of bioactive factors presented in the lipid phase of human milk during the first 6 months of lactation [pg/ml]

From: Distribution of bioactive factors in human milk samples

Factors Lipid phase [L]
Water fraction [L-WF] Lipid fraction [L-LF]
1–3 months 4–6 months p- values
1–3 vs 4–6 mo
1–3 months 4–6 months p- values
1–3 vs 4–6 mo
CD40 22.87 ± 7.36 34.11 ± 6.67 0.019 22.98 ± 7.87 29.80 ± 0.01 0.1330
EGF 828.48 ± 480.11 1851.26 ± 456.69 < 0.0001 375.25 ± 129.18 669.11 ± 197.70 < 0.0001
MCP-1 13.02 ± 3.49 21.41 ± 9.71 0.0245 5.07 ± 0.69 10.67 ± 6.01 0.0020
RANTES 3.13 ± 0.73 4.34 ± 0.59 < 0.0001 3.65 ± 1.86 2.37 ± 0.0 0.2031
  1. CD40 cluster of differentiation 40; EGF epidermal growth factor; MCP-1 macrophage chemokine protein-1; RANTES regulated on activation, normal T cell expressed and secreted; mo months