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Table 4 Infant outcome by site and feeding practice

From: Infant feeding practices at routine PMTCT sites, South Africa: results of a prospective observational study amongst HIV exposed and unexposed infants - birth to 9 months

Feeding practices measured at 5 week visit*

HR for infant HIV or death amongst HIV-exposed infants

Longitudinal feeding practice (0-12 weeks)#

HR for postnatal HIV or infant death amongst HIV-exposed infants

 

N

Total no. HIV/dead in each area (%)

HR (95% CI)

 

N

Total no. HIV/dead in each area (%)

HR (95% CI)

Paarl (IMR 40/100)

 

20

 

Paarl

   

   EFF

48

3 (6.2%)

Referent HR = 1

Avoiding BF (NBF)

98

4 (4.1%)

Referent HR = 1

   EBF

15

4 (26.7)

4.7 (1.0, 20.9)

EBF and stopping before 12 weeks

7

1 (14.3%)

1.9 (0.2, 1.5)

   MBF

15

5 (33.3)

5.7 (1.4, 23.9)

MBF(l)

10

3 (30%)

4.3 (1.2, 16.0)

   MFF

56

8 (14.3)

2.4 (0.6, 8.9)

    

Rietvei (IMR 99/1000)

 

46

 

Rietvei

   

   EFF

14

2(14.3%)

6.6 (1.7, 25.4)

Avoiding BF (NBF)

66

14 (21.2%)

5.6 (1.8, 17)

   EBF

19

7 36.8%)

2.3 (0.4, 14.0)

EBF and stopping before 12 weeks

11

3 (27.3%)

2.8 (0.6, 13.1)

   MBF

64

20 (31.2%)

5.6 (1.6, 18.7)

MBF(l)

38

7 (18.4%)

2.7 (1.0, 7.2)

   MFF

63

17 (27%)

4.7 (1.4, 16.1)

    

Umlazi (IMR 60/1000)

 

51

 

Umlazi

   

   EFF

41

8 (19.5%)

1.2 (0.1, 11.9)

Avoiding BF (NBF)

44

7 (15.9%)

4.0 (1.2, 13.7)

   EBF

14

1 (7.1%)

3.3 (0.8, 12.5)

EBF and stopping before 12 weeks

8

1 (12.5%)

1.9 (0.7, 5.2)

   MBF

84

24 (28.6%)

5.0 (1.5, 16.5)

MBF(l)

29

4 (13.8%)

2.1 (0.6, 6.7)

   MFF

55

18 (32.7%)

5.8 (1.7, 19.7)

 
  1. Footnote: EFF = exclusive formula feeding; EBF = exclusive breastfeeding; MBF = mixed breastfeeding; MFF = mixed formula feeding (no breast) NBF = avoiding all breastfeeding. * Feeding practices defined as per Table 2 and measured over previous 96 hours at 5 week visit. Note feeding data not available on all infants who died or were lost to follow-up, thus numbers in table are slightly less than the total expected (expected N = 883 total sample, 665 HIV-exposed infants and N = 156 HIV infected or died). Note: Background IMR per site as follows; Paarl IMR 40/1000; Rietvlei IMR 99/1000 and Umlazi IMR 60/1000 at the time of the study. The numbers of women practicing longitudinal exclusive breastfeeding between 0-12 weeks was very low; thus no data on this group are presented under the longitudinal feeding data in Table 4.