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Archived Comments for: A new paradigm for depression in new mothers: the central role of inflammation and how breastfeeding and anti-inflammatory treatments protect maternal mental health

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  1. Would this be possible?

    Nikki Lee, Maternal, Child, and Family Health

    7 July 2007

    Would it be possible then, to treat some forms of depression with an anti-inflammatory drug, such as ibuprofen?

    Competing interests

    None declared

  2. Ibuprofen could be an adjunct treatment

    Kathleen Kendall-Tackett, University of New Hampshire

    7 August 2007

    I wouldn't consider anti-inflammatories, such as ibuprofen, frontline treatments for depression. Nor would recommend trying to treat depression with ibuprofen alone. However, it could be a helpful adjunct. Ibuprofen, like aspirin, lowers risk of cardiovascular disease--most likely because it is anti-inflammatory. Because these same processes are present in depression, anti-inflammatory NSAIDs could potentially help. They also lower pain, which can indirectly lower depression risk.

    Competing interests