The use of prescription medications and non-prescription medications during lactation in a prospective Canadian cohort study

Table 3 10 most common prescription medications used by mothers while breastfeeding at 6 months (n = 1948) compared to non-breastfeeding mothers (n = 639) with most common reasons for medication use in the CHILD cohort study

	Breastfeeding mothers			Non-breastfeeding mothers
Prescription medication	Reported reason for use*	Mothers who used medication for specified reason		Reported reason for use*	Mothers who used medication for specified reason
		%	n		%	n
domperidone	Lactation disorder	98.15	106	Lactation disorder	88.89	8
norethisterone	Contraception	100	84	Contraception	100	9
levothyroxine	Hypothyroidism	97.44	76	Hypothyroidism	88	22
amoxicillin	Sinusitis	21.43	6	No Data
	Urinary tract infection	10.71	3
	Pharyngitis	10.71	3
	Respiratory tract infection	7.14	2
	Ear infection	7.14	2
citalopram	Depression	77.78	21	Depression	81.82	9
citalopram	Anxiety	37.04	10	Anxiety	36.36	4
salbutamol	Asthma	80.77	21	Asthma	88.89	8
cephalexin	Mastitis	44.44	8	No data
	Breast infection	11.11	2
	Infection	11.11	2
antibacterial drug name unknown	Reason not given	100	17	Reason not given	100	3
sertraline	Depression	58.82	10	Depression	88.89	8
	Anxiety	41.18	7	Anxiety	33.33	3
	Postpartum depression	11.76	2	Anxiety	33.33	3
hydrocortisone	Eczema	38.46	5	No data

* Reason for medication use was ontologized (assigned an ontology/controlled vocabulary with hierarchy)
**The combination of medications used and indication that was only used once was removed from the table
***Indications related to lactation were bolded

ISSN: 1746-4358